DNAC physical connectivity is important to bring up the interfaces and pass the initial connection checks and NTP checks for DNAC to continue the application install. While doing the initial setup, I would highly encourage to setup CIMC first so that you can configure the DNAC interfaces before starting the switch side connectivity and configuration. My physical setup with single DNAC is shown below.
The first fiber link (in my case IP 10.10.5.2) is the cluster link connecting to a switch, if you have multiple DNAC, all of their cluster link should be connected via L2, sharing Virtual IP. configuration on the DNAC side is shown below.
The second fiber link is used for enterprise connectivity (in my case IP 10.10.6.2), this will also be used for accessing your DNAC GUI or CLI. the config on the DNAC side is shown below.
switch side config is shown below
switchport trunk allowed vlan 6
switchport mode trunk
ip address 10.10.6.4 255.255.255.0
DNAC Side IP Config
The green cable is CIMC (IP 10.10.1.2) and the gray cable (10.10.2.2) is for out of band management which is not configured yet.
Once the setup is done right, while installing DNAC you will hit a bug CSCvi01378, however this is cosmetic and the workaround will work just fine, if your connectivity is correct.
Now you are ready to move on with the DNAC install, after install you will be able to access DNAC home page and ready to work.
Hope you enjoy reading it a much as I enjoyed writing it.